Senior Lab Scientist
Company: HemoShear Therapeutics
Location: Charlottesville
Posted on: May 14, 2022
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Job Description:
HemoShear Therapeutics is a clinical stage company developing
new treatments for patients with rare metabolic disorders. We apply
our deep understanding of complex diseases to discover breakthrough
treatments for our proprietary pipeline. We also partner with
biopharma companies to accelerate their drug discovery and
development programs in liver diseases, gout, and metabolic
disorders. We are implementing a new vision for how advanced
biological systems can yield new insights that improve health and
quality of life for patients in need.
We currently have a new opening for a Senior Lab Scientist .
SUMMARY OF POSITION
The Senior Lab Scientist will design, develop, and perform
biological assays while also analyzing data and presenting their
results as a member of HemoShear's proprietary and collaborative
partnership drug discovery program teams. The Senior Lab Scientist
will be expected to work independently in a self-directed manner as
well as collaboratively alongside a larger assay team. Additional
responsibilities include performing cell culture, molecular biology
experiments and protein production and purification. The role will
require training of colleagues in the developed techniques to
support the HemoShear assay team. The position involves teamwork,
high levels of communication, and ensuring scientific excellence.
The Senior Lab Scientist will work closely with the program team
leaders to ensure that all work stays on schedule and is completed
according to HemoShear's standards. This role will report to the
Lab Manager and will based in the Charlottesville, VA office.
KEY DUTIES AND RESPONSIBILITIES
Work collaboratively with colleagues in Exploratory Biology and
Discovery Biology to provide functional expertise
Develop and optimize cell-free and cell-based assays in medium- to
high-throughput (96/384-well) formats
Generate stable cell lines and verify expression or lack of
expression using molecular biology endpoints, western blots and
reporter assays using various readouts (e.g., qPCR, fluorescence,
luminescence, mass spectrometry, etc.)
Protein production, purification, and characterization
Partner with chemistry and biology teams to troubleshoot through
technical and scientific challenges to deliver critical data
Present results, conclusions, and implications to project teams and
senior management
Assist development and implementation of biological assays needed
to support the drug discovery project
REQUIREMENTS
B.S. with 15+ years' experience, or M.S. with 10+ years life
sciences experience
Experience in cellular and molecular biology (DNA/RNA extraction,
RT-qPCR, qPCR, primer design), cell-based assays (sterile tissue
culture techniques, transfection, transduction, maintaining,
subcloning, and banking cells)
Experience measuring protein expression levels, turn-over and
synthesis rates: western blot, ELISA, reporter assays, etc.
Experience using automated imaging systems, plate readers and
associated software
Demonstrated technical proficiency, scientific creativity,
independent thought, and ability to effectively collaborate with
others
Excellent written and oral communication skills
HemoShear offers a full range of comprehensive benefits to support
the well-being of our employees. Career growth and development
opportunities are important to the culture at HemoShear. If your
background matches the required experience, please apply directly
to our website at www.hemoshear.com.
HemoShear Therapeutics is an equal opportunity employer. Qualified
candidates will receive consideration for employment without regard
to race, color, religion, sex, sexual orientation, gender identity,
national origin, disability or protected veteran status.
Keywords: HemoShear Therapeutics, Charlottesville , Senior Lab Scientist, Healthcare , Charlottesville, Virginia
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