Senior Lab Scientist

Company: HemoShear Therapeutics
Location: Charlottesville
Posted on: May 14, 2022

Job Description:

HemoShear Therapeutics is a clinical stage company developing new treatments for patients with rare metabolic disorders. We apply our deep understanding of complex diseases to discover breakthrough treatments for our proprietary pipeline. We also partner with biopharma companies to accelerate their drug discovery and development programs in liver diseases, gout, and metabolic disorders. We are implementing a new vision for how advanced biological systems can yield new insights that improve health and quality of life for patients in need.

We currently have a new opening for a Senior Lab Scientist .

SUMMARY OF POSITION

The Senior Lab Scientist will design, develop, and perform biological assays while also analyzing data and presenting their results as a member of HemoShear's proprietary and collaborative partnership drug discovery program teams. The Senior Lab Scientist will be expected to work independently in a self-directed manner as well as collaboratively alongside a larger assay team. Additional responsibilities include performing cell culture, molecular biology experiments and protein production and purification. The role will require training of colleagues in the developed techniques to support the HemoShear assay team. The position involves teamwork, high levels of communication, and ensuring scientific excellence. The Senior Lab Scientist will work closely with the program team leaders to ensure that all work stays on schedule and is completed according to HemoShear's standards. This role will report to the Lab Manager and will based in the Charlottesville, VA office.

KEY DUTIES AND RESPONSIBILITIES

Work collaboratively with colleagues in Exploratory Biology and Discovery Biology to provide functional expertise
Develop and optimize cell-free and cell-based assays in medium- to high-throughput (96/384-well) formats
Generate stable cell lines and verify expression or lack of expression using molecular biology endpoints, western blots and reporter assays using various readouts (e.g., qPCR, fluorescence, luminescence, mass spectrometry, etc.)
Protein production, purification, and characterization
Partner with chemistry and biology teams to troubleshoot through technical and scientific challenges to deliver critical data
Present results, conclusions, and implications to project teams and senior management
Assist development and implementation of biological assays needed to support the drug discovery project

REQUIREMENTS

B.S. with 15+ years' experience, or M.S. with 10+ years life sciences experience
Experience in cellular and molecular biology (DNA/RNA extraction, RT-qPCR, qPCR, primer design), cell-based assays (sterile tissue culture techniques, transfection, transduction, maintaining, subcloning, and banking cells)
Experience measuring protein expression levels, turn-over and synthesis rates: western blot, ELISA, reporter assays, etc.
Experience using automated imaging systems, plate readers and associated software
Demonstrated technical proficiency, scientific creativity, independent thought, and ability to effectively collaborate with others
Excellent written and oral communication skills

HemoShear offers a full range of comprehensive benefits to support the well-being of our employees. Career growth and development opportunities are important to the culture at HemoShear. If your background matches the required experience, please apply directly to our website at www.hemoshear.com.

HemoShear Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Keywords: HemoShear Therapeutics, Charlottesville , Senior Lab Scientist, Healthcare , Charlottesville, Virginia