The Department of Chemistry at the University of Virginia
invites applications for a postdoctoral research-associate position
to work in the lab of Marcos Pires, Associate Professor. Of
particular interest at this time is experience with animal
experiments and microbiology.
The Postdoctoral Research Associate will work as part of a team
of scientists to design and synthesize small molecules, peptides,
or express proteins that label live bacterial cells. The focus is
primarily on synthetic components and analysis in bacterial cells.
Research duties will include protein expression and purification
from bacteria and subsequent modification (bioconjugation) and
peptide synthesis in solution phase and/or solid phase.
Responsibilities may include bacterial cell-based assay development
and optimization, elucidation of biologically relevant
targets/mechanisms of action, flow cytometry analysis, and confocal
microscopy. Postdoctoral Fellow will publish their findings in high
impact, peer-reviewed journals and be co-inventors on patents
related to their work.
The Pires research group has recently demonstrated that several
cell wall biosynthetic enzymes display broad substrate promiscuity.
Their research team has pioneered a novel strategy to graft haptens
onto bacterial surfaces to recruit endogenous antibodies with the
ultimate goal of enlisting the immune system to clear bacterial
infections. Moving forward, the Pires laboratory will develop a
transformative class of cell wall probes that reveal key features
of cell wall sensing and remodeling dynamics in live cells. Their
advances in this area demonstrate that their research team can be
highly competitive as they expand their methodologies to elucidate
how bacterial cell walls are detected by the human immune system
and how cell wall structural modifications control bacterial drug
APPLICATION PROCEDURE: Apply online at https://uva.wd1.myworkdayjobs.com/UVAJobs
and attach a maximum one-page cover letter, a curriculum vitae,
maximum three-page statement of their research interests,
experience, and plans, and the contact information for three
individuals who can provide professional reference letters. The
University will perform background checks on all new hires prior to
APPLICATION DEADLINE: Review of applications will begin on March
9, 2020, but the position will remain open until filled. Starting
date is flexible, but the anticipated start date is June 1, 2020.
The University will perform background checks on all new hires
prior to employment.
This is a one-year appointment; however, the appointment may be
renewed for two additional one-year terms, contingent upon
available funding and satisfactory performance.
For questions about the position, please contact Marcos Pires,
Associate Professor, at firstname.lastname@example.org.
For questions about the application, please contact Rich
Haverstrom, Faculty Search Advisor, at email@example.com
For more information on the benefits available to postdoctoral
associates at UVA, visit postdoc.virginia.edu and
The University of Virginia, including the UVA Health System and
the University Physician's Group are fundamentally committed to the
diversity of our faculty and staff. We believe diversity is
excellence expressing itself through every person's perspectives
and lived experiences. We are equal opportunity and affirmative
action employers. All qualified applicants will receive
consideration for employment without regard to age, color,
disability, gender identity or expression, marital status, national
or ethnic origin, political affiliation, race, religion, sex
(including pregnancy), sexual orientation, veteran status, and
family medical or genetic information.