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Research Scientist, Hirschi Lab

Company: University of Virginia
Location: Charlottesville
Posted on: June 7, 2021

Job Description:

The Department of Cell Biology at the University of Virginia School of Medicine is seeking a Research Scientist to work in the laboratory of Dr. Karen Hirschi. The focus of their research is to understand the molecular regulation of blood and blood vessel development. Within this focus, the Hirschi Lab is establishing a collaborative initiative: The Developmental Genomics Center. This Center will be the scientific hub for collaborative research between clinicians, bioinformaticians and experimental biologists to pursue cutting-edge research in developmental biology. The Hirschi lab will manage and coordinate the center, being the point-of-contact for collaborative investigators and performing experimental research.


The Research Scientist will serve as the lead bioinformatician for the Developmental Genomics Center, and support the experimental research performed in the Center under the supervision of the Principal Investigator (PI - Dr. Hirschi) and other research staff. This individual must be highly collaborative and well versed in the analysis of one or more high-throughput sequencing or "omics" approaches, such as RNA single-cell sequencing approaches. The incumbent will be expected to: independently perform bioinformatics data analysis using internally developed tools, as well as open source and third-party genomics software and prediction algorithms; develop computational approaches including deep learning to analyze genomic, transcriptomic and proteomic patterns associated with developmental biological models; and work with other computational and experimental lab members and collaborators to turn new findings into experimentally and computationally testable hypotheses.

The incumbent will attend bi-weekly meetings with the PI to discuss progress in the Developmental Genomics Center, lab management issues, and results from experiments. In addition, the incumbent will attend bi-weekly Hirschi Lab Meetings and the Developmental Genomics Center Seminar Series. The incumbent will work under supervision, independently and ethically, document all research data appropriately, and assist other members of the lab and Center.


Education: Ph.D. or terminal degree in computer science, physical sciences or biological sciences with demonstrated proficiency in bioinformatics, data analysis and visualization (R and/or Python, lineage projection programs such as PHATE).

Experience: Skills in working with large datasets and developing tools and algorithms for analysis of large datasets is required. Background in genomics, MS-based proteomics or network science is a plus. Preferably at least three years of experience with computational biology and data analysis.

The ideal candidate will be a highly-motivated individual with a history of excellent work ethic, attention to detail, organization and communication skills, ability to learn new skills and work both independently and collaboratively.


For questions about the application process please contact Bethany Case, Recruiter. For further information regarding this position, please contact Dr. Karen Hirschi, Professor of Cell Biology, via email at Application review will begin immediately, and remain open until filled.

Please apply through Workday, and search for "Research Scientist, Hirschi Lab". Complete an application online and attach a cover letter (addressed to Dr. Karen Hirschi), contact information for three references, and a CV/resume all into the resume submission field, multiple documents can be submitted into this one field. Internal applicants must apply through their UVA Workday profile. The successful candidate will pass a criminal background check. This is a restricted position; continuation is dependent on funding and satisfactory performance.

The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician's Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.

Keywords: University of Virginia, Charlottesville , Research Scientist, Hirschi Lab, Other , Charlottesville, Virginia

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